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Researchers use enriched stem cells to speed up healing process in bone fractures
Wednesday, 15 June 2011 15:11

Researchers use enriched stem cells to speed up healing process in bone fracturesAmericans who are turning 65 or older this year may have a greater risk of bone fractures, which can lead to significant injury and discomfort. According to a study presented at the 93rd Annual Meeting of the Endocrine Society in Boston, stem cell therapy that utilizes the bone-generating hormone IGF-I can help mend bones in fractures that are having difficulty healing normally.

Lead investigator Anna Spagnoli and her colleagues from the University of North Carolina at Chapel Hill reported that incomplete fracture healing affects about 600,000 people in North America each year.

"The problem is even more serious in children with osteogenesis imperfecta, or brittle bone disease, and in elderly adults with osteoporosis," Spagnoli explained. "Their fragile bones can easily and repeatedly break, and bone graft surgical treatment is often not successful or feasible."

She and her team suggested the use of stem cells enriched with IGF-I, which was used in a mouse model and helped the cells in the broken bones repair the fracture. This enabled the healing process to go more quickly, leading to greater strength in the affected bone.
 

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